Due to the great difference of physical properties between CFRP and TC4 materials， the cutting performance matching of CFRP/TC4 stack components was poor. There were some problems such as interface damage and CFRP hole wall damage that were difficult to control during drilling. In view of the above problems， the drilling experiments of CFRP/TC4 stacks were carried out by using variable parameter pecking drilling technology， variable parameter drilling technology and constant parameter drilling technology. The thrust force， interface quality， chip morphology of TC4 and hole wall quality of CFRP under different process conditions were compared and analyzed. The results show that the thrust force of TC4 obtained by variable parameter pecking drilling process is significantly higher than that under the other two processes， and short ribbon and short spiral chips are produced. The diameter at the exit and entrance of the CFRP stack are closer to the nominal diameter， and the hole wall defects are less， and the surface roughness is relatively low.